The First 48 Hours
Immediately after a liver transplant, you will wake up in the Intensive Care Unit (ICU). The new liver typically begins functioning within hours, and the medical team monitors liver enzymes, bile production, and blood clotting factors closely to confirm the graft is working.
Hospital Stay
Most patients spend seven to fourteen days in hospital following a liver transplant. During this time, you will be moved from the ICU to a regular ward, begin eating soft foods, and start walking with physiotherapy support. Immunosuppressant medications are started immediately to prevent rejection.
The First Three Months
This is the highest-risk period for rejection and infection. You will attend clinic visits two to three times per week. Blood tests are done at every visit to monitor liver function and drug levels. It is essential to avoid contact with people who are unwell and to follow strict food hygiene.
Returning to Normal Life
Most patients can return to light work within three to six months. Physical exercise is encouraged and gradually built up. Driving is typically permitted after six to eight weeks. With good adherence to medications and regular follow-up, over 90% of liver transplant recipients lead a normal quality of life beyond five years.
Long-term Medications
Immunosuppressant medications such as tacrolimus and mycophenolate are lifelong. These prevent the body from rejecting the donor liver. Regular monitoring ensures doses are adjusted appropriately over time.